Blockade of Fas-dependent apoptosis by soluble Fas in LGL leukemia
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چکیده
منابع مشابه
Blockade of Fas-dependent apoptosis by soluble Fas in LGL leukemia.
Altered expression of the Fas-Fas ligand apoptotic pathway leads to lymphoproliferative and autoimmune diseases. In lpr/lpr mice and children with autoimmune lymphoproliferative syndrome, defective apoptosis is due to Fas mutations. Large granular lymphocyte (LGL) leukemia is a clonal lymphoproliferative disorder associated with rheumatoid arthritis. Leukemic LGLs are resistant to Fas-dependent...
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ژورنال
عنوان ژورنال: Blood
سال: 2002
ISSN: 1528-0020,0006-4971
DOI: 10.1182/blood.v100.4.1449.h81602001449_1449_1453